Example
Are there risks associated with the live yellow fever vaccine?
Step 1: Break up this research question into two or three main concepts. Ignore extraneous words.
Step 2: Conduct an initial search with these words, and quickly scan the results.
Step 3: Using information from your initial search, add synonyms, acronyms, and variant spellings.
(risks OR safety OR adverse events OR side effects) AND (yellow fever) AND (live vaccine)